Intshayelelo

Kwiilabhoratri zanamhlanje, ii-autosampler vials ziye zaba sisixhobo esiphambili ekuqinisekiseni ukuba imifuniselo iyasebenza, ichanekile kwaye ithembekile.Ingaba kuhlalutyo lweekhemikhali, ukubeka iliso kokusingqongileyo okanye uphando lweklinikhi, i-autosampler vials idlala indima ebalulekileyo, isebenza ngokubambisana neebhotile ze-autosampler ukuqokelela nokugcina iisampuli ngokukhawuleza nangokuchanekileyo. Lo msebenzi ozenzekelayo awuphuculi kakhulu ukusebenza kakuhle kovavanyo kunye nokunciphisa impazamo yabantu, kodwa ukwaqinisekisa ukuhambelana kwesampulu kunye nomgangatho.

Nangona kunjalo, ngaphandle koncedo oluziswa yi-autosampler vials, kusekho iingxaki eziqhelekileyo ezinokuthi zenzeke ngexesha lokusetyenziswa kwazo. Ezi ngxaki zinokuchaphazela ingqibelelo yesampulu okanye ukuchaneka kweziphumo zovavanyo, ngaloo ndlela zichaphazela ukuthembeka kwayo yonke inkqubo yokuhlalutya.

Ngoko ke, injongo yeli nqaku kukuxoxa ngeengxaki eziqhelekileyo ezinokuthi zihlangabezane nazo xa usebenzisa i-autosampler vials kunye nokubonelela iilabhoratri ngoluhlu lwezisombululo ezisebenzayo zokuqinisekisa inkqubo yokuhlola egudileyo kunye nokwandisa ukuchaneka kohlalutyo kunye nokuthembeka kweziphumo.

Amagqabantshintshi eMibuzo eQho ukubuzwa malunga ne-Autosampler Vials

1. Umnqwazi webhotile uyavuza okanye awuvali kakuhle

Ukusebenza kokutywinwa kwe-cap kuchaphazela ngokuthe ngqo ukusebenza kwe-autosampler vials. Ukuba i-cap ayivalwanga ngokufanelekileyo okanye isitywina sinesiphene, isampuli inokuvuza okanye ikhuphe, okukhokelela ekulahlekeni kwesampulu, ukubola kwamacandelo okanye ukungcoliseka kwangaphandle. Ukutywinwa kakubi kunokukhokelela kumoya okanye ezinye izinto zangaphandle ezingena kwibhotile, ezichaphazela umgangatho wesampuli.

2. Iibhotile ze-autosampler ezaphukileyo okanye ezonakalisiweyo

Iibhotile ze-autosampler zihlala zenziwe ngeglasi, leyo, nangona ikhemikhali izinzileyo kunye nokungafihli, iyakwazi ukuphuka ngexesha lokuthutha, ukuphatha okanye ukucoca. Nayiphi na impembelelo yangaphandle, utshintsho lweqondo lokushisa, okanye ukuhluka koxinzelelo kunokubangela ukuba ibhotile okanye umlomo uphuke, kwaye ibhotile yesampuli ephukileyo ingakhokelela ekuvuzeni isampuli okanye umonakalo, okukhokelela ekulahlekelweni kwedatha yovavanyo. Kwangaxeshanye, iziqwenga zeglasi ezaphukileyo zinokubeka ingozi yokhuseleko kubasebenzi baselabhoratri, ukwandisa ukunxiba kunye nokukrazula kwezixhobo kunye nobunzima bokusebenza.

3. Usulelo lwesampulu

Ukukhethwa kwezinto ezingafanelekanga kwi-autosampler vials okanye ii-caps ezingcolileyo zingakhokelela ekungcolisekeni kwesampuli. Iikhemikhali ezithile zinokusabela ngempahla yebhotile okanye zibhengezwe ngodonga lwebhotile, ezichaphazela ukucoceka kwesampuli. Ukongezelela, iindlela zokucoca ezingafanelekanga okanye iindawo zokugcina zingakhokelela kwintsalela okanye ukukhula kwebhaktheriya ngaphakathi kwebhotile, enokungcolisa isampuli. Iisampulu ezingcolileyo zinokuchaphazela ngokuthe ngqo ukuthembeka kovavanyo, okukhokelela kwidatha egqwethekileyo kunye nokuchaphazela ukuchaneka kweziphumo zohlalutyo.

4. Iimeko ezingafanelekanga zokugcina iibhotile ze-autosampler

Iimeko zokugcina i-autosampler vials zibaluleke kakhulu ekusebenzeni kwazo kunye nomgangatho wesampuli. Iimeko ezingafanelekanga zokugcina (umzekelo, ubushushu obuphezulu, ukufuma okuphezulu, ilanga elithe ngqo, okanye iindawo ezimanzi ngokugqithisileyo) zinokubangela ukuwohloka kwempahla yebhotile okanye kuthintele ukuzinza kweesampuli ngaphakathi kwebhotile, kwaye ezinye iisampuli ezinobuthathaka bekhemikhali zinokusabela okanye zibole ngenxa yeemeko ezingafanelekanga zokugcina; ngelixa iimeko zokugcinwa kakubi zingakhokelela ekuguqulweni kwebhotile, ukungaphumeleli kwetywina, okanye ukugqabhuka. Iisampulu zinokonakala okanye zingcoliseke kwiindawo ezingafanelekanga, ekugqibeleni zichaphazele ukuqinisekiswa kovavanyo kunye nokuchaneka kwedatha.

Ezi ziintlobo ezintlanu eziqhelekileyo zeengxaki ezinokuchaphazela ukusebenza kwe-autosampler vials kwaye kwinqanaba elithile kufuneka lichaphazele ukuchaneka kweziphumo zovavanyo.

Izisombululo kunye neeNgcebiso

1. Isisombululo 1: Qinisekisa ukutywinwa kwe-cap

Qwalasela ii-cap seal ukuqinisekisa ukuba azinxibi okanye ziwohloke, ngakumbi xa zisetyenziswa rhoqo. Khetha ii-caps ezingcono zomgangatho wokuqinisekisa ukusebenza kokutywinwa okuzinzile, kunye nokuqinisekisa indlela echanekileyo ye-torquing, kwaye ugweme amandla amaninzi xa ufaka ii-caps, ezinokuchaphazela imilo okanye umsebenzi wetywina.

Iicaps ezinezitywina ezikhethekileyo zingasetyenziswa, zibonelela ngesitywina esingcono kwaye zinciphise ukuvuza kwegesi okanye ukuphuphuma kwesampulu. Eminye imifuniselo echanekileyo ephezulu inokufuna ukusetyenziswa kweendlela zokutywina ezongezelelweyo zokuqinisekisa ukuqulathwa okupheleleyo kwesampulu, ngakumbi kwizinto eziguqukayo.

2. Isisombululo 2: Khetha izinto ezifanelekileyo zebhotile kunye neenkcukacha

Khetha izinto ezifanelekileyo kwi-autosampler vials ngokohlobo lwesampulu esetyenziswe kuvavanyo. Ukukhetha izinto ezizinzile kwiikhemikhali kubaluleke kakhulu ukuba isampuli iyasebenza kakhulu okanye iyaguquguquka. Iibhotile zeglasi zifanelekile kuhlalutyo oluninzi lwesiqhelo, kodwa kwiisampuli eziphantsi kweemeko ezithile ezigqithisileyo (umzekelo, izisombululo ze-acidic, i-alkaline okanye iindawo ezinobushushu obuphezulu, njl.), iibhotile ze-polypropylene okanye ezinye izinto ezicwangcisiweyo ezikhethekileyo zinokuthi zifaneleke ngakumbi.

Khangela ngamaxesha athile ukubonakala kweebhotile ukuqinisekisa ukuba akukho zintanda okanye omnye umonakalo, ngakumbi ngexesha lokuthutha kunye nokugcinwa. Iibhotile zeglasi ziyakwazi ukuphuka ngenxa yamandla angaphandle, kwaye ukuhlolwa rhoqo kunokunceda ukukhusela ukuvuza okanye ukulahleka kweesampuli ngenxa yomonakalo webhotile. Gwema ukushisa okanye iimpembelelo ngexesha lokugcinwa, okunokwandisa ubomi bebhotile.

3. Isisombululo 3: Ukucocwa kunye nokugcinwa

Ukucocwa kwee-autosampler vials linyathelo elibalulekileyo ekuqinisekiseni ukuba iisampuli azingcoliswanga. Ukucoca ngokucokisekileyo iibhotile rhoqo, ngakumbi emva kokutshintshwa kwesampuli okanye emva kokuba iibhotile zigcinwe ixesha elide. Kuphephe ukungcolisa iisampulu ezintsha ngeekhemikhali ezishiyekileyo, izinyibilikisi okanye izinto zokucoca.

Xa ucoca, hlambulula ibhotile ngokucokisekileyo nge-solvent efanelekileyo. Emva kokucoca, qiniseka ukuba iibhotile zeglasi zomile ngokupheleleyo, mhlawumbi ngokusebenzisa ilaphu elicocekileyo elingalukwanga okanye ukomisa umoya. Kwakhona kubalulekile ukucoca ii-caps kunye neentamo zeebhotile ngexesha lokucoca ukukhusela izinto ezingcolileyo ekuchaphazela umgangatho weesampuli.

4. Isisombululo 4: Nika ingqalelo kwiimeko zokugcina

Iibhotile ze-Autosampler kufuneka zigcinwe kwindawo efanelekileyo, zigweme iimeko ezingathandekiyo ezifana nokushisa, umswakama okanye ukukhanya kwelanga. Indawo efanelekileyo yokugcina indawo eneqondo lokushisa eliphakathi kunye nomswakama ophantsi, okuthintela ukuwohloka kwempahla yebhotile okanye ukuphazamiseka komgangatho wesampuli.

Ukuze ugweme ukuguquguquka kweqondo lokushisa kunye nemiphumo yokufuma, cinga ukusebenzisa iibhokisi zokugcina ezikhethekileyo okanye ukupakishwa kokukhusela. Ezi phakheji zikhusela ngokufanelekileyo iibhotile kwiinguqu kwimeko yangaphandle kwaye ziqinisekisa ukuba umgangatho ugcina ukusebenza kwawo kunye nokutywinwa ngexesha lokugcinwa. Kwiisampuli ezifuna ukugcinwa ixesha elide, kucetyiswa ukuba kusetyenziswe iikhabhinethi zokugcina i-cryogenic okanye izixhobo zokugcina ezihambelana noxinzelelo lomoya.

Izisombululo ezingentla ziyakwazi ukuphepha ngokufanelekileyo iingxaki ezinokuthi zenzeke ekusebenziseni i-autosampler vials kunye nokuphucula ukuthembeka kweemvavanyo kunye nokuchaneka kohlalutyo lwesampulu. Ukuqinisekisa ukutywinwa kwe-cap, ukukhetha izinto ezifanelekileyo zebhotile kunye neenkcukacha, ukucoca rhoqo kunye nokugcinwa, kunye nokuqinisekisa ukuhambelana komgangatho kunye nezixhobo zizo zonke izinto eziphambili ekuqinisekiseni ukuba iimvavanyo zihamba kakuhle.

Amanqaku awongezelelweyo kunye neengcebiso

1. Ukuhlolwa rhoqo kunye nokulinganisa izixhobo

Ukuhlola rhoqo iinxalenye ezidibeneyo ze-autosampler kunye nebhotile ukuze uqinisekise ukuba zonke iikhonkco kunye nabafowunelwa azinxitywanga okanye ziwohloke. Ii-autosamplers zihlala zineendawo ezininzi ezihambayo ezinokuguga ngokusetyenziswa, okubangela ukuba iibhotile zingahlangani ngokufanelekileyo okanye zingatywinwa ngokufanelekileyo. Ngoko ke, ukuhlolwa rhoqo kunye nokulinganisa kuyinyathelo eliyimfuneko ukuze kuqinisekiswe ukuchaneka kwezixhobo.

Ukongeza kwi-calibration yezixhobo zomatshini, ukuchaneka kwesampulu kufuneka kulinganiswe ngamaxesha athile ukuqinisekisa ukuhambelana nokuthembeka ekusebenzeni kwayo. Ukulinganisa rhoqo akuphuculi nje ukuchaneka kweesampuli, kodwa kwandisa ubomi bezixhobo.

2. Ukulandelela iingcebiso zomthengisi

Qonda kwaye ulandele imiyalelo yokusetyenziswa enikezelwe ngumvelisi okanye isixhobo autosampler zosula elungileyo lusizi ukusasaza okulungileyo lusizi. Ezi zikhokelo zihlala ziqulethe ulwazi malunga neyona ndlela ilungileyo yokusebenzisa izixhobo, ukugcinwa kwamaxesha, kunye neengxaki eziqhelekileyo kunye nezisombululo ezinokudibana nazo ngexesha lokusetyenziswa. Iingcebiso zabavelisi zezona zenzo zibalaseleyo ezisekwe kuphando lwexesha elide kunye novavanyo, ke ngoko ukulandela iingcebiso ezibonelelwe ngumenzi ngokusondeleyo kuya kuqinisekisa ukusebenza kakuhle kwezixhobo kunye neebhotile.

Iintlobo ezahlukeneyo zeebhotile zeglasi kunye nepeyinti yepeyinti ye-matte ezenzekelayo inokuba nokwahlukana kweenkcukacha zoyilo, ngokweemfuno ezithile zomenzi ukuba zisetyenziswe, kungekuphela nje ukuphepha ukungasebenzi kakuhle okuziswa kukusebenza okungafanelekanga, kodwa nokuqinisekisa ukuchaneka kwedatha kwinkqubo yovavanyo.

3. Ulawulo oluhle lwebhetshi

Kwiilabhoratri ezisebenzisa inani elikhulu leebhotile ze-autosampler, ulawulo olululo lwebhetshi lubalulekile. Iibhetshi ezahlukeneyo zeebhotile zinokuba nentlukwano encinci kwizinto eziphathekayo, ubungakanani okanye inkqubo yokuvelisa, ngoko ke kubalulekile ukwahlula ngokuthe ngqo phakathi kweebhetshi xa uzisebenzisa ukuphepha ukubhidanisa umthombo kunye nokunciphisa ukuchaneka kweesampuli.

Oku kunokwenziwa ngenkqubo yokulawula iilebhile okanye ngokusebenzisa i-middle-batch coding ukuqinisekisa ukuba ibhetshi nganye yeebhotile zeglasi isetyenziswa ngokuchanekileyo ngokweenkcukacha zayo kunye nemiqathango yokusetyenziswa kwayo. Kufuneka kwakhona kuthathelwe ingqalelo ukurekhoda ixesha lokusetyenziswa kunye nemeko yeebhotile ukwenzela ukuba imbali kunye nokusetyenziswa kweebhotile kunokulandelwa xa kufuneka.

4. Iimathiriyeli ezizezinye kunye nobuchwepheshe obutsha

Njengoko itekhnoloji ihambela phambili, izixhobo ezitsha ze-autosampler ziyaqhubeka nokuphuma, uninzi lwezixhobo ezitsha zodonga lweglasi yemveli kunye neplastiki inenzuzo ngakumbi. Umzekelo, ubushushu obuphezulu kunye nezixhobo ezidityanisiweyo ezinokumelana neekhemikhali zinokumelana neemeko zovavanyo ezingqongqo, ezifanelekileyo kuluhlu olubanzi lweemeko zesicelo. Kwezinye izicelo ezikhethekileyo, unokuqwalasela izinto ezintsha ze-autosampler vials ukuphucula ukuchaneka kunye nokhuseleko lwemifuniselo.

Izinto ezithile ezidityanisiweyo, ezinokumelana ne-thermal kunye ne-corrosion ephezulu, zinokuhlala zizinzile kumaqondo obushushu aphezulu okanye kwindawo eqinileyo ye-asidi kunye ne-alkali. Ukongeza, ezinye iiplastiki ezisebenza kakhulu azinayo nje ukuchasana kweekhemikhali ezigqwesileyo, kodwa zinciphisa ngempumelelo ukusabela phakathi kwesampulu kunye nodonga lwebhotile, olulungele ukwenziwa kweesampulu kwiindawo ezigqithisileyo.

Ngala manyathelo ongezelelweyo kunye neengcebiso, iilebhu zinokuphucula ngakumbi ukusebenza kwe-autosampler vials, ukubanceda ukuba bakhulise ukusebenza kakuhle kwelebhu, bandise ubomi besixhobo, banciphise iimpazamo, kwaye baqinisekise iqondo eliphezulu lokuchaneka kwedatha yabo yelebhu.

Ukuqukumbela

Iibhotile ze-autosampler zidlala indima ebalulekileyo kwiilabhoratri zanamhlanje, kwaye ukusetyenziswa kwazo ngokufanelekileyo kunye nokugcinwa kwazo kuhambelana ngokuthe ngqo nokuchaneka kunye nokuthembeka kweziphumo zovavanyo. Ngokukhetha okufanelekileyo, ukuhlolwa rhoqo kunye nokugcinwa, ukutywinwa, ukuqina kunye nokulungelelaniswa kwe-autosampler vials kunokuqinisekiswa, kwaye iingxaki eziqhelekileyo zinokugwenywa, ngaloo ndlela kuphuculwe ukusebenza kakuhle kweemvavanyo kunye nokuthembeka kweziphumo.

Kuphela ngokukhethwa kwenzululwazi kunye nokugcinwa ngokucophelela, ii-autosampler iivials zinokunika umdlalo opheleleyo kwiinzuzo zabo eziphezulu, ukunceda iilabhoratri ukuba zigqibezele imisebenzi yohlalutyo lomntu ngokufanelekileyo nangokuchanekileyo, ngaloo ndlela zibonelela ngenkxaso yedatha enamandla yophando lwezenzululwazi kunye nokuveliswa kwemveliso.